Every year around 200,000 couples are affected by unwanted childlessness in Germany. In roughly half the cases, the cause can be attributed to a fertility problem on the part of the man. Infections and inflammations frequently lead to impaired male fertility. MIBIE studies how infections and inflammations of the genito-urinary tract can lead to infertility and in so doing, combines fundamental research with clinical application. For instance, improved methods of examination have already made it possible to identify illness-related mechanisms, to distinguish between infectious and inflammatory causes and to target the treatment accordingly. In order to continue the joint interdisciplinary research, application has been made to set up a DFG research group. MIBIE will also continue to contribute its expertise to a German-Australian International Research Training Group (IRTG). The research cluster was also able to attract a DFG Workshop for Early Career Investigators, which was conducted at Justus Liebig University Giessen in May 2015.