The rotational direction of molecules (chirality) is a key element affecting their behaviour in chemical reactions, and, in the case of biomolecules, their medical efficacy. Although there are certain complex methods that describe chirality, it is not yet understood how the rotational direction of the atomic structure of molecules affects the dynamics of molecular electrons. The LOEWE research cluster ELCH brings together scientists working in experimental and theoretical disciplines within the subject areas of physics and chemistry with a view to decoding the dynamics of the electron system of chiral systems and the basic principles of their genesis. Besides tackling these fundamental questions, the researchers hope to develop a highly efficient method for analysing molecular chirality that may be used, for instance, in the development of pharmaceuticals.