Since January 1, 2022, three new LOEWE focus areas have received research funding from Hesse:
The LOEWE focus area "GreenDairy - Integrated animal-plant-agricultural ecosystems" on the topic of "sustainability" under the leadership of the Justus Liebig University in Gießen examines the functionality and sustainability of two types of milk production systems. It is hoped that the results will provide important impetus for agricultural system research and recommendations for advisory and practice. The scientific coordinator is Professor Dr. Andreas Gattinger. Project partner is the University of Kassel.
"FLOW FOR LIFE" is the name of the new LOEWE focus, which is led by the Technical University of Darmstadt. The research focus is on drug development. Despite extensive tests and animal experiments, the majority of new drugs are not approved because they are judged to be insufficiently effective or even toxic when tested on humans. Organs artificially produced in the laboratory are intended to test the effectiveness and toxicity of active substances on human cells outside the body. The scientists of the new LOEWE focus want to optimize this test method by developing controllable and measurable artificial supply networks for an adequate supply of nutrients and oxygen to organ-like three-dimensional cell structures. Prof. Dr. Ulrike Nuber and Prof. Dr. Jeannette Hussong are the two scientific coordinators.
The new LOEWE focus "ACLF I - Pathogenetic Mechanisms of Acute-On-Chronic Liver Failure" with the lead management of the Goethe University Frankfurt deals with the clinical picture of liver cirrhosis and the acute organ failure that often results from it, the ACLF (acute-on-chronic liver failure ). The origin of ACLF is still insufficiently researched. Therefore, the scientists of the LOEWE focus want to investigate different mechanisms and the interaction between individual organs in the development of ACLF. The aim is to develop new diagnostic tests and therapeutic approaches. Scientific coordinator is Prof. Dr. med. Jonel Trebicka. Project partners are the Fraunhofer-Institut für Molekularbiologie und Angewandte Ökologie IME in Gießen, the Georg-Speyer-Haus in Frankfurt and the Paul-Ehrlich-Institutin Langen.
The decision was made last summer by the LOEWE Administrative Commission based on the assessments of an external expert and the recommendations of the LOEWE program advisory board. The selected research projects will receive a total of 18 million euros from the state program for a period of four years. Among the LOEWE research-initiatives of this 14th funding season is a project that was selected as part of the topic-specific call for proposals on the topic of "sustainability".