One of the most important goals of the programme is a permanent anchoring of LOEWE-funded research in the universities and research institutions of Hesse. One example of how this can successfully occur is the DFG collaborative research centre 1319 ELCH that has now been established in 2018 under the lead management of the University of Kassel. This is the outgrowth of the LOEWE research cluster ELCH, which was funded in the period from 2013 to 2016. And there are other similar developments worthy of note. For example, the first Fraunhofer Institute to be located in Frankfurt may soon become a reality. The requisite conditions for this development are currently being put into place. Following the conclusion of the second ongoing funding period of the LOEWE research centre Translational Medicine and Pharmacology (TMP, lead management: Goethe University Frankfurt), it is planned for the TMP division of the Fraunhofer Institute IME to be transferred to the basic financing of the Fraunhofer Society. In 2023, the TMP should move into a new building on the Niederrad Campus of the University Hospital Frankfurt. Last year, the great expectations surrounding the LOEWE research centre CASED, which has received funding since 2008, became a reality. In September 2017, the establishment of the Darmstadt Center for Research in Security and Privacy (CRISP) was announced – which was based on the previous LOEWE research centre CASED among other antecedents. CRISP will become a permanent national research centre for applied cybersecurity. This has been agreed by the different organisations participating in CRISP - the Fraunhofer Society, TU Darmstadt, and the Darmstadt University of Applied Sciences. The German Federal Ministry of Education and Research and the Hessian Ministry of Science and the Arts have agreed to the support and financing of the new centre. The topping out ceremony for the new Fraunhofer building for bioresources in Giessen that took place in May 2018 should also receive mention here as one more step on the way to the establishment of a new Fraunhofer Institute for bioresources. The new research complex should be completed in the middle of 2019. The basis of the planned Fraunhofer Institute which will be the first in the Mittelhessen region – is the LOEWE research centre for Insect Biotechnology and Bioresources (ZIB), which has developed successfully in a cooperative undertaking involving the Justus Liebig University Giessen (JLU), the TH Mittelhessen University of Applied Sciences (THM) and the Fraunhofer Institute for Molecular Biology and Applied Ecology IME.