The LOEWE Cluster iCANx (Cancer - Lung (Disease) Crosstalk: Tumor and Organ Microenvironment) invites all interested parties to the fifth iCANx Minisymposium on May 11, 2023, from 2:30 to 5:30 pm. The event will take place at the Justus Liebig University in Giessen.

Four outstanding scientists will present their research results in the field of lung cancer research on the following topics:

Professor Dr. med. Sebastian Kobold, University Hospital Munich: „How T cells drive metastatic spread in lung cancer and beyond“

Dr. Meike J. Saul, Technical University of Darmstadt: „The role of miR-574-5p in inflammation and cancer.“

Dr. Markus E. Diefenbacher, Julius-Maximilians-University Würzburg: „Exploiting tumour intrinsic vulnerabilities via the ubiquitin system.“

Professor Dr. Manuel Kaulich, Goethe-University Frankfurt am Main: „Assigning function to genes by unbiased 2D and 3D CRISPR screens.“

The lectures will be held in English.

iCANx Minisymposium, 11.5.2023, 14.30 – 17.30 Uhr

Justus-Liebig-Universität Gießen

BFS Seminar Room 17.1 and 17.22

Schubertstr. 81

Gießen

The goal of the multidisciplinary LOEWE focus PriOSS (Principles of Surface Based Synthesis Strategies) is to develop fundamental models for on-surface synthesis and to create a toolbox for this new methodology, as it has existed for classical synthesis in solution for centuries. In order to get closer to this goal, the LOEWE-PriOSS Symposium at Schloss Rauischholzhausen will bring together researchers with different expertise in the fields of physics, chemistry and theory to address the following topics, among others:

• Reactions and assembly processes of molecules on surfaces
• Manipulation of single molecules
• Development of new functional materials with special properties and potential applications.

Since the deposition and positioning of molecular structures on surfaces, e.g. for functional assemblies, is difficult, nanostructures are now increasingly successfully fabricated directly on surfaces; this is referred to as "on-surface synthesis". This approach is particularly interesting for two-dimensional (2D) materials, which per se require a surface as a support structure. However, the selective synthesis of such complex functional elements still poses a particular challenge. While synthesis in solution can draw on almost 200 years of experience and mature methods, the concepts of on-surface synthesis are still in their infancy. The two-dimensional (2D) nature of the surface opens up special possibilities for controlling reaction processes and offers the possibility of specifically building nanoarchitectures from atomic/molecular building blocks.

The LOEWE research cluster FLOW FOR LIFE is organizing a mini symposium on June 15, 2022 from 6:00 p.m. to 8:00 p.m. at the TU Darmstadt and online on the topic: “Building tissues requires analytical and constructive approaches – insights into bone regeneration and building of a vessel network”

Building tissues for clinical purpose (to reconstruct or replace diseased or lost tissue) and for preclinical purpose (to generate human tissues that can be applied for drug toxicity and efficacy tests) requires both, analytical and constructive, approaches: Analyses of how tissues develop and regenerate form the basis for ideas and experiments on the use of cellular and synthetic materials for tissue (re-)construction.

Lectures:

• Catherine Picart (CEA Grenoble and Université Grenoble-Alpes): “Bioactive medical devices for bone regeneration”
• Claudio Franco (Instituto de Medicina Molecular, Universidade de Lisboa): “How to build an efficient network of vessels”.

Location: Campus Botanical Garden, TU Darmstadt, Building B2/61

For Zoom link, please contact mbecker@bio.tu-darmstadt.d

Our decade is characterized by the term Big Data, which is used in many different areas of application. Common to all of them is the generation of complex, but above all large amounts of data, whereby traditional software for analysis, but also previously used storage systems are no longer sufficient in the short to medium term. Since the methods for data generation are becoming more and more inexpensive, the number of data sets is constantly growing across different diverse disciplines. This applies above all to sensor data collected from monitoring systems, climate data, social media or the Internet of Things, but also to other areas such as particle physics and personalized medicine. With the associated volume of data generation, the vast data amounts typically grow exponentially and are estimated to double every 24 months. In turn, archiving and reading them requires new layers and approaches in the storage hierarchy.

New current approaches for the problem of long-term archiving include molecular storage of information. Particularly, the storage in the form of inorganic molecules or DNA. The latter is specifically valuable as it has the potential for higher storage capacity and longer durability compared to traditional storage media. Therefore, molecular media could make the constant copying of data completely unnecessary and thus increase data security. The objective of the first international conference on Data Storage in Molecular Media (DSMM) is to bring together all players to discuss advances and efforts to reduce the cost and retrieval time of information stored in molecular media. 

The Conference is led by Georges Hattab, Dominik Heider and Anke Becker, scientist of the LOEWE-Research-Initiative MOSLA.